ANTIHYPERTENSIVE AND CAPDIOPROTECTIVE EFFI CACY OF BISOPROLOL IN MIDDLEAGED AND ELDERLY PATIENTS WITH ARTERIAL HYPERTENSION

Authors Prikhoda I.V.




Nechaeva O.V




Nechaev N.A.




Abstract The aim of the study was to clinical effi cacy and security of the application in bisoprolol on treatment in middle-aged and elderly patients with arterial hypertension. There were examined 50 patients with arterial hypertension. Thirty one patients with arterial hypertension were treated with bisoprolol 5 - 10 mg daily. All examinations were carried out before and 4 weeks after bisoprolol therapy. According to our results, bisoprolol signifi cantly reduced blood pressure (BP), the pressure load and hypertension time index during 24 hours, day and nigth time. Bisoprolol can also normalized BP variability and diurnal BP rythm in addition to signifi cant antihypertensive action. The effi cacy and security of clinical application were determined.
Key words effi ciency ; security ; bisoprolol ; arterial hypertension ;
References Rekomendacii Ukrains"koi asociacii kardiologiv z profilaktiki ta likuvannia arterial"noi gipertenzii: Posibnik do Nacional"noi programi profilaktiki i likuvannia arterial"noi gipertenzii, tretie vidannia. - K.: 2004. - 83 s.

Svishchenko E.P., Kovalenko V.N. Gipertonicheskaia bolezn". Vtorichnye gipertenzii Pod red. V.N. Kovalenko. - K.: Libid", 2002. - 504s.

Sirenko Iu.M. Arterial"na gipertenziia: Posibnik dlia likariv. - K.: Morion, 2001. - 95 s.

Sirenko Iu.M. Arterial"na gipertenziia: Posibnik dlia likariv. - K.: Morion, 2002. - 204 s.

Guidelines Committee - 2003. European Society of Hypertension - European Society of Cardiology guidelines for the management of arterial hypertension J. Hypertension. - 2003. - Vol.21. - P.1011-1053.

Hansson L., Zanchetti A., Garruthers S.G. et al. Effects of intensive blood pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomized trial Lancet. - 1998. - Vol. 351. - P.1755-1763.

Hansson L., Lindholm L.H., Ekbom T. et al. Randomized trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morfidity in Swedish Trial of Old Patients with Hypertension - 2 study Lancef. - 1999. - Vol. 354. - P.1751-1756.

The sixth report of tht Joint. National Committee on prevention, detection, evolution and Creatment of high blood pressure Arch. Intern. Ned. - 1997. - Vol. 157 (21). - P.2413-2446.

1999 World Heals Organization International Society of Hypertension Guidelines for the management of Hypertension Guidelines Subc. J. Hypertension. - 1999. - Committee Vol. 17 (2). - P.151-153.

White W. Blood pressure monitoring in cardiovascular medicine and therapeutics. - New Jersey: Humana Press, 2001. - 308p.

First page 119
Last page 122
Volume 6
Year 2009
Title of Journal Pedagogika, psihologia ta mediko-biologicni problemi fizicnogo vihovanna i sportu=PEDAGOGICS, PSYCHOLOGY, MEDICAL-BIOLOGICAL PROBLEMS OF PHYSICAL TRAINING AND SPORTS
Article PDF, full text
Journal HTML, Contents