IL-6 реакція на глікемічний індекс під час відновлення після фізичних вправ
DOI:
https://doi.org/10.15561/18189172.2015.0607Ключові слова:
вправи, глікемічний, індекс, вуглеводиАнотація
Мета : Це дослідження вивчало вплив їжі з різним глікемічним індексом (ГІ) на плазму IL-6 концентрації і метаболізму глюкози після максимальних скорочень м'язів розгиначів коліна. Матеріал : 10 здорових чоловіків виконували по 5 підходів в 10 ексцентричних скороченнях (120% в 1 максимальному повторенні). Суб'єкти були рандомізовані і приймали GI напій [високий ГІ, низький ГІ (вага 15% в обсязі; 3 г / кг маси тіла)] або плацебо 3 рази протягом 10 хвилин після тренування. Потім знову на 50 і 110 хвилині в період відновлення. Проби крові брали перед тренуванням і після 0.60, 180 хвилин і 24 годин відновлення. Результат : Концентрація в плазмі IL-6 у групі з високим ГІ був менший, ніж в групах з середнім та низьким ГІ. IL-6, як правило, значно збільшується після тренування в часі відновлення в 3 групі (всі р <0,05) за винятком протягом 24 годин (P = 1,00). Крім того, спостерігалося істотне розходження для IL-6 між плацебо в групі з високим ГІ протягом 3 годин після тренування (P = 0,016). Концентрація в сироватці креатинкиназа в групі з високим ГІ була меншою, ніж у групах з низьким і середнім ГІ. Креатинкиназа був значно підвищений у весь час і в усіх точках при відновленні в 3 групах (всі р<0,05) протягом 1 години після тренування в групі з високим ГІ (P = 0,31), але за винятком того, що ні зазначалося жодної істотної відмінності в креатинкиназа між групами. Висновки : В цілому, споживаючи вуглеводи з високим ГІ під час відновлення після тренувань послаблюється IL-6 концентрація в плазмі.Посилання
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<p>Beaton L.J., Tarnopolsky M.A., Phillips S.M. Contraction-induced muscle damage in humans following calcium channel blocker administration. <i>Journal of Physiology</i>, 2002, vol.544(Pt 3), pp. 849–859.</p>
<p>Burke L.M., Kiens B., Ivy J.L. Carbohydrates and fat for training and recovery. <i>Journal of Sports Sciences</i>, 2004, vol.22, pp. 15–30.</p>
<p>Cockburn E., Robson-Ansley P., Hayes P.R. Effect of milk volume consumed on the attenuation of exercise-induced muscle damage. <i>European Journal of Applied Physiology</i>, 2011, vol.51, pp. 618-625.</p>
<p>Dasu M.R., Devaraj S., Jialal I. High glucose induces IL-1beta expression in human monocytes: mechanistic insights. <i>American Journal of Physiology, Endocrinal Metabolism</i>, 2007, vol.293(1), pp. E337–E346.</p>
<p>Depner C.M., Frederickson S.J., Rhodes K. <i>Post-exercise carbohydrates increase the magnitude of the inflammatory response</i>. Seattle, WA. American College of Sports Medicine. 2009, 120 p.</p>
<p>Dhindsa S., Tripathy D., Mohanty P. Differential effects of glucose and alcohol on reactive oxygen species generation and intranuclear nuclear factor- kappaB in mononuclear cells. <i>Metabolism: clinical and experimental</i>, 2004, vol.53(3), pp. 330–334.</p>
<p>Dickinson S., Hancock D.P., Petocz P. High-glycemic index carbohydrate increases nuclear factorkappaB activation in mononuclear cells of young, lean healthy subjects. <i>American Journal of Clinical Nutrition</i>, 2008, vol.87(5), pp. 1188–1193.</p>
<p>Esposito K., Nappo F., Marfella R. Inflammatory cytokine concentrations are acutely increased by hyper glycemian in humans: role of oxidative stress. <i>Circulation</i>, 2002, vol.106, pp. 2067- 2072.</p>
<p>Eston R.G., Mickleborough J., Baltzpolous V. Eccentric activation and muscle damage: biomechanical and physiological considerations during downhill running. <i>British Journal of Sports Medicine</i>, 1995, vol.292, pp. 89 – 94.</p>
<p>Febbraio M.A., Steensberg A., Keller C. Glucose ingestion attenuates interleukin-6 release from contracting skeletal muscle in humans. <i>Journal of Physiology</i>, 2003, vol.549(Pt 2), pp. 607–612.</p>
<p>Gonzalez F., Rote N.S., Minium L. Obese reproductive-age women exhibit a proatherogenic inflammatory response during hyperglycemia. <i>Obesity</i>, 2007, vol.15, pp. 2436-2444.</p>
<p>Hirose L., Nosaka K., Newton M. Changes in infl ammatory mediators following eccentric exercise of the elbow flexors. <i>Exercise Immunology Reviews</i>, 2004, vol.10, pp. 75–90.</p>
<p>Jenkins D.J., Wolever T.M., Taylor R.H. Glycemic index of foods: a physiological basis for carbohydrate exchange. <i>The American Journal of Clinical Nutrition</i>, 1981, vol.34, pp. 362–366.</p>
<p>Kirwan J.P., O'Gorman D.J., Cyr-Campbell D. Effects of a moderate glycemic meal on exercise duration and substrate utilization. <i>Medicine and Science in Sports and Exercise</i>, 2001, vol.33, pp. 1517–1523.</p>
<p>Louis E., Raue U., Yang Y. Time course of proteolytic, cytokine, and myostatin gene expression after acute exercise in human skeletal muscle. <i>Journal of Applied Physiology</i>, 2007, vol.103(5), pp. 1744–1751.</p>
<p>MacIntyre D.L., Sorichter S., Mair J. Markers of inflammation and myofibrillar proteins following eccentric exercise in humans. <i>European Journal of Applied Physiology</i>, 2001, vol.84, pp. 180-186.</p>
<p>Miles M.P., Depner C.M., Kirwan R.D. Influence of macronutrient intake and anthropometric characteristics on plasma insulin after eccentric exercise. <i>Metabolism: clinical and experimental</i>, 2010, vol.59, pp. 1456-1464.</p>
<p>Miles M.P., Pearson S.D., Andring J.M. Effect of carbohydrate intake during recovery from eccentric exercise on interleukin-6 and muscle-damage markers. <i>International Journal of Sport Nutrition and Exercise Metabolism</i>, 2007, vol.17, pp. 507–520.</p>
<p>Mohanty P., Hamouda W., Garg R. Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes. <i>Journal of Clinical Endocrinology and Metabolism</i>, 2000, vol.85(8), pp. 2970–2973.</p>
<p>Nieman D.C., Johanssen L., Lee J.W. Immune response to heavy exertion. <i>Journal of Applied Physiology</i>, 1998, vol.82, pp. 1385-1394.</p>
<p>Nieman D.C., Kernodle M.W., Henson D.A. The acute response of the immune system to tennis drills in adolescent athletes. <i>Research Quarterly for Exercise and Sport</i>, 2000, vol.71, pp. 403-408.</p>
<p>Nieman D.C., Davis J.M., Henson D.A. Muscle cytokine mRNA changes after 2.5 h of cycling: influence of carbohydrate. <i>Medicine and Science in Sports and Exercise</i>, 2005, vol.37(8), pp. 1283–1290.</p>
<p>Nieman D.C., Davis J.M., Henson D.A. Carbohydrate ingestion influences skeletal muscle cytokine mRNA and plasma cytokine levels after a 3-h run. <i>Journal of Applied Physiology</i>, 2003, vol.94(5), pp. 1917–1925.</p>
<p>Paulsen G., Benestad H.B., Strøm-Gundersen I. Delayed leukocytosis and cytokine response to high-force eccentric exercise. <i>Medicine and Science in Sports and Exercise</i>, 2005, vol.37(11), pp. 1877–1883.</p>
<p>Peake J.M., Nosaka K., Muthalib M. Systemic infl amatory responses to maximal versus submaximal lengthening contractions of the elbow flexors. <i>Exercise Immunology, Reviews</i>, 2006, vol.12, pp. 72–85.</p>
<p>Peake J.M., Suzuki K., Hordern M. Plasma cytokine changes in relation to exercise intensity and muscle damage. <i>European Journal of Applied Physiology</i>, 2005, vol.95, pp. 514-521.</p>
<p>Petersen A.W., Pedersen B.K. The anti-inflammatory effect of exercise. <i>Journal of Applied Physiology</i>, 2005, vol.98, pp. 1154 – 1162.</p>
<p>Raastad T., Risoy B.A., Benestad H.B. Temporal relation between leukocyte accumulation in muscles and halted recovery 10–20 h after strength exercise. <i>Journal of Applied Physiology</i>, 2003, vol.95(6), pp. 2503–2509.</p>
<p>Smith L.L., Anwar A., Fragen M. Cytokines and cell adhesion molecules associated with high-intensity eccentric exercise. <i>European Journal of Applied Physiology</i>, 2000, vol.82, pp. 61-67.</p>
<p>Stevenson E., Williams C., Nute M. The effect of the glycemic index of an evening meal on the metabolic responses to a standard high glycemic index breakfast and subsequent exercise in men. <i>International Journal of Sport Nutrition and Exercise Metabolism</i>, 2005, vol.15, pp. 308–322.</p>
<p>Steensberg A., Fischer C.P., Keller C. IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans. <i>American Journal of Physiology, Endocrinal Metabolism</i>, 2002, vol.285, pp. E433-E437.</p>
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2015-06-28
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Hasani S, Supaporn S, Mehranpour A, Witid M. IL-6 реакція на глікемічний індекс під час відновлення після фізичних вправ. Pedagogics, psychology, medical-biological problems of physical training and sports. 28, Червень 2015;19(6):41-7. доступний у10.15561/18189172.2015.0607
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